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What disease is caused by trisomy 21?

Asperger syndrome

cri-du-chat (cat meowing syndrome)

Down syndrome

Patau syndrome

Most cases of Down syndrome are caused by trisomy 21. Occasionally, the extra chromosome #21 or a portion of it is attached to another chromosome in the egg or sperm; this may cause "translocation Down syndrome." This is the only form of Down syndrome that may be inherited from a parent.

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100%

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11

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3%

90%

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33

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8%

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88%

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135

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2%

86%

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36

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5%

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20

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11%

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80%

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10180

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79%

12%

24

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14%

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78%

7%

14

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23%

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76%

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17

the United Kingdom

14%

2%

75%

5%

136

Italy

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0%

75%

16%

12

the United States

13%

6%

73%

2%

134

Austria

7%

14%

71%

7%

14

Denmark

10%

10%

70%

10%

10

Republic of Ireland

5%

5%

68%

15%

38

India

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12%

67%

5%

164

France

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20%

66%

0%

15

the Philippines

19%

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57%

0%

21

Nigeria

28%

20%

48%

4%

25

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