Mars colonisation is a hype topic. What is the biggest threat for those wishing to take a part in a journey to Mars?

low temperatures
lack of oxygen
poor gravity
cosmic rays
The only efficient protection against high energetic cosmic radiation, one we are granted with, is Earth's magnetic field. Both during a long flight to Mars and through the stay on the planet, that did not form electromagnetic field, astronauts would be exposed to ionization.
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Very interesting!
reach: rather globalastronauticsastronomyMarsphysicsplanetsSolar Systemtechnology

Answers by country

low temperatures
lack of oxygen
poor gravity
cosmic rays
answers
flagthe Netherlands
6%
10%
6%
75%
48
flagAustralia
5%
19%
6%
67%
100
flagFrance
7%
21%
10%
60%
38
flagRepublic of Ireland
6%
31%
3%
59%
32
flagAustria
6%
28%
5%
56%
160
flagGreece
6%
23%
6%
56%
30
flagGermany
9%
27%
6%
54%
1155
flagUnknown
11%
23%
11%
53%
52
flagCanada
8%
29%
8%
50%
68
flagPoland
10%
30%
8%
48%
20006
flagthe United States
8%
32%
8%
47%
560
flagthe United Kingdom
9%
33%
9%
47%
284
flagSwitzerland
14%
24%
9%
47%
115
flagPakistan
11%
32%
11%
43%
53
flagthe United Arab Emirates
14%
28%
14%
39%
28
flagMalaysia
12%
33%
12%
37%
24
flagIndia
10%
37%
13%
36%
1061
flagthe Philippines
10%
47%
9%
32%
106
flagNigeria
8%
52%
8%
32%
25
flagGhana
0%
56%
20%
20%
25