Which infectious agent causes diseases that are the most difficult to cure?

bacteria
virus
fungus
prion
All known prion diseases affect the struc­ture of the brain or other neural tissue and all are cur­rent­ly un­treat­able and uni­ver­sal­ly fatal. This includes bovine spongi­form en­cephalopa­thy (BSE, also known as "mad cow dis­ease") in cattle and Creutzfeldt–­Jakob disease (CJD) in humans.

Answers distribution

bacteria
virus
fungus
prion
answers
flagCzech Republic
4%
17%
4%
73%
23
flagUkraine
0%
20%
8%
71%
35
flagFrance
4%
22%
4%
69%
49
flagRepublic of Ireland
5%
18%
6%
68%
76
flagGermany
4%
21%
5%
66%
206
flagItaly
3%
23%
6%
66%
30
flagPoland
6%
22%
5%
64%
18589
flagPakistan
5%
25%
6%
62%
59
flagAustria
8%
29%
0%
62%
24
flagUnknown
8%
25%
5%
61%
134
flagCanada
6%
29%
2%
61%
92
flagIndia
2%
28%
6%
60%
388
flagMalaysia
0%
30%
8%
60%
23
flagAustralia
16%
19%
3%
58%
31
flagLithuania
3%
27%
3%
58%
29
flagthe United Kingdom
4%
33%
6%
55%
529
flagthe Netherlands
6%
31%
6%
53%
60
flagthe United States
5%
33%
6%
52%
918
flagNorway
12%
25%
10%
52%
40
flagthe Philippines
11%
33%
3%
50%
78

Gender

men63%
women64%
bacteria
5%
7%
virus
23%
21%
fungus
7%
5%
prion
63%
64%

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Which infectious agent causes diseases that are the most difficult to cure?
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